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| PCVXPCVXVaxcyte, Inc. | Vaxcyte, Inc. | $61.42 | $9.7B |
| KRYSKRYSKrystal Biotech, Inc. | Krystal Biotech, Inc. | $316.08 | $9.4B |
| TGTXTGTXTG Therapeutics, Inc. | TG Therapeutics, Inc. | $55.88 | $8.6B |
| ARWRARWRArrowhead Pharmaceuticals, Inc. | Arrowhead Pharmaceuticals, Inc. | $58.81 | $8.3B |
| ALKSALKSAlkermes plc | Alkermes plc | $45.04 | $7.6B |
| BLCOBLCOBausch + Lomb Corporation | Bausch + Lomb Corporation | $19.28 | $6.9B |
| MMSIMMSIMerit Medical Systems, Inc. | Merit Medical Systems, Inc. | $92.50 | $5.5B |
| STVNSTVNStevanato Group S.p.A. | Stevanato Group S.p.A. | $19.52 | $5.3B |
| PTCTPTCTPTC Therapeutics, Inc. | PTC Therapeutics, Inc. | $62.14 | $5.2B |
| CRSPCRSPCRISPR Therapeutics AG | CRISPR Therapeutics AG | $51.58 | $5.0B |