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| RVMD | Revolution Medicines, Inc. | $184.41 | $39.2B |
| MRNA | Moderna, Inc. | $58.62 | $23.3B |
| JAZZ | Jazz Pharmaceuticals plc | $251.88 | $15.8B |
| EXEL | Exelixis, Inc. | $55.31 | $13.9B |
| MDGL | Madrigal Pharmaceuticals, Inc. | $543.83 | $12.5B |
| BMRN | BioMarin Pharmaceutical Inc. | $58.44 | $11.3B |
| CORT | Corcept Therapeutics Incorporated | $93.38 | $10.0B |
| QGEN | Qiagen N.V. | $40.39 | $8.3B |
| CAI | Caris Life Sciences, Inc. | $15.50 | $4.4B |
| RNA | Atrium Therapeutics, Inc. | $12.18 | $208.3M |