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| CGON | CG Oncology Inc. | $71.57 | $6.3B |
| SRRK | Scholar Rock Holding Corporation | $49.93 | $6.0B |
| XENE | Xenon Pharmaceuticals Inc. | $65.72 | $5.2B |
| CELC | Celcuity Inc. | $89.70 | $4.4B |
| ADPT | Adaptive Biotechnologies Corporation | $21.88 | $3.5B |
| IDYA | IDEAYA Biosciences, Inc. | $35.57 | $3.4B |
| IRON | Disc Medicine, Inc. | $74.22 | $2.8B |
| TARS | Tarsus Pharmaceuticals, Inc. | $57.97 | $2.5B |
| ZLAB | Zai Lab Limited | $20.83 | $2.4B |
| AAPG | Ascentage Pharma Group International | $19.30 | $1.8B |