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| SRRK | Scholar Rock Holding Corporation | $56.96 | $6.8B |
| CGON | CG Oncology Inc. | $73.47 | $6.5B |
| XENE | Xenon Pharmaceuticals Inc. | $59.89 | $5.8B |
| CELC | Celcuity Inc. | $95.82 | $4.7B |
| ADPT | Adaptive Biotechnologies Corporation | $24.43 | $3.9B |
| TARS | Tarsus Pharmaceuticals, Inc. | $89.87 | $3.9B |
| IDYA | IDEAYA Biosciences, Inc. | $38.99 | $3.7B |
| IRON | Disc Medicine, Inc. | $77.53 | $3.0B |
| ZLAB | Zai Lab Limited | $26.10 | $2.9B |
| AAPG | Ascentage Pharma Group International | $17.25 | $1.6B |