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| ACHVACHVAchieve Life Sciences, Inc. | Achieve Life Sciences, Inc. | $6.49 | $667.8M |
| NAUTNAUTNautilus Biotechnolgy, Inc. | Nautilus Biotechnolgy, Inc. | $3.24 | $412.3M |
| AVIRAVIRAtea Pharmaceuticals, Inc. | Atea Pharmaceuticals, Inc. | $4.04 | $324.0M |
| SGMTSGMTSagimet Biosciences Inc. | Sagimet Biosciences Inc. | $9.58 | $312.1M |
| ARCTARCTArcturus Therapeutics Holdings Inc. | Arcturus Therapeutics Holdings Inc. | $9.84 | $279.7M |
| VNDAVNDAVanda Pharmaceuticals Inc. | Vanda Pharmaceuticals Inc. | $4.01 | $242.5M |
| IMRXIMRXImmuneering Corporation | Immuneering Corporation | $3.73 | $241.3M |
| TRDATRDAEntrada Therapeutics, Inc. | Entrada Therapeutics, Inc. | $4.41 | $171.7M |
| FHTXFHTXFoghorn Therapeutics Inc. | Foghorn Therapeutics Inc. | $2.00 | $118.8M |
| VYGRVYGRVoyager Therapeutics, Inc. | Voyager Therapeutics, Inc. | $1.74 | $107.2M |