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| GKOSGKOSGlaukos Corporation | Glaukos Corporation | $178.88 | $10.6B |
| PCVXPCVXVaxcyte, Inc. | Vaxcyte, Inc. | $60.43 | $9.5B |
| TGTXTGTXTG Therapeutics, Inc. | TG Therapeutics, Inc. | $54.17 | $8.3B |
| ARWRARWRArrowhead Pharmaceuticals, Inc. | Arrowhead Pharmaceuticals, Inc. | $58.02 | $8.2B |
| OSCROSCROscar Health, Inc. | Oscar Health, Inc. | $30.99 | $8.0B |
| ACLXACLXArcellx, Inc. | Arcellx, Inc. | $115.07 | $6.7B |
| TFXTFXTeleflex Incorporated | Teleflex Incorporated | $136.29 | $5.8B |
| MMSIMMSIMerit Medical Systems, Inc. | Merit Medical Systems, Inc. | $93.30 | $5.6B |
| PTCTPTCTPTC Therapeutics, Inc. | PTC Therapeutics, Inc. | $60.59 | $5.1B |
| CRSPCRSPCRISPR Therapeutics AG | CRISPR Therapeutics AG | $49.39 | $4.8B |